Picks up where the last episode left off. Meredith attempts to work with Addison Shepherd. George is pimped out to relay the hospital gossip back to Webber. Meredith and Cristina relate at Emerald City Bar about what dating their respective...

A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his own medical concerns. Izzie and Cristina...

Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged m...

Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwh...

Izzie tries to get George to find the courage to ask Meredith out. All of the interns are in awe when a woman comes in with a record breaking tumor, but it is so far advanced that the woman's prognosis is not good. Now that Bailey know...

Meredith realizes that she must take on a lot more responsibility when she is told that her mother needs to sign over all of her assets to her. As Izzie prepares to have a party for her boyfriend Hank (the scale of which is unknown to Mered...

While George is feeling a little less masculine because of the way Izzie and Meredith have been treating him (like a sister), Izzie is assigned to a patient about to lose all of his masculinity. Cristina, true to her competitive spirit, sho...

When a bike race leaves one pedestrian brain dead, interns Cristina and Izzie face an emotional crisis of conscience: how long does one wait before they start harvesting his organs? Cristina is all detached professionalism , but ever-hopefu...

The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile, Meredith puts her career on the line to save a newborn in the hospital nursery; while taking on the responsibility of an object that...

Meredith Grey enrolls in a rigorous surgical residency program at Seattle Grace Hospital where she will spend the next 7 years. Hours into the program, Meredith finds out her one-night-stand is her boss. Meanwhile, George is chosen to perfo...

A fed up Nancy squeals to the DEA to bust the tunnel while she plays it cool with Esteban. Embracing rehab, Celia sets out to make amends with her family. Andy succumbs to Maria's advances, and later comes clean to Doug. Shane impresse...

Nancy finds out more about the tunnel; Doug pursues Maria; Celia experiences rehab;

Nancy discovers the tunnel is being used for more than drugs. Esteban allays her fears and her nagging headache with a powerful remedy. Celia's family stages an intervention, forcing her into rehab. Andy locates Maria and brings her ac...

Nancy and Esteban struggle to fit each other into their busy schedules. Having discovered Shane's new fantasies and Silas's new girlfriend, Nancy is forced to have a talk with both of her sons. Meanwhile, Celia grows more desperat...

Esteban and Nancy's spontaneous date ends in near violence. Andy and Doug successfully smuggle their first customer across the border. Silas reveals to Lisa that he grows pot, and she offers to let him do business in the back of her st...